Principal Clinical Scientist
Posted 1 day ago by Alignerr
Negotiable
Undetermined
Remote
Birmingham, England, United Kingdom
Summary: The Principal Clinical Scientist (AI Training) role involves leveraging extensive clinical trial expertise to influence AI systems that interpret clinical data and regulatory submissions. This fully remote contract position is designed for experienced clinical scientists who aim to impact patient outcomes significantly. The role includes collaboration with leading AI research labs to ensure that AI models handle clinical evidence appropriately. Candidates will be responsible for designing clinical trial protocols and providing expert feedback on AI-generated analyses.
Key Responsibilities:
- Design and critically review clinical trial protocols used to generate high-quality, regulator-ready training datasets for AI systems
- Interpret and audit clinical trial results to ensure accuracy, consistency, and alignment with regulatory standards (FDA, EMA, or equivalent)
- Evaluate AI-generated clinical analyses for scientific soundness and regulatory relevance
- Provide structured, expert feedback that shapes how AI models reason about clinical trial design, data, and outcomes
- Help establish the gold standard for how AI understands and communicates clinical evidence
Key Skills:
- Senior-level clinical scientist with hands-on experience designing clinical trial protocols for regulatory submission
- Deep expertise interpreting clinical data for regulatory agencies such as the FDA, EMA, or equivalent bodies
- Strong grounding in clinical research methodology, biostatistics, or translational science
- Naturally detail-oriented with a high standard for clinical evidence
- Comfortable working independently in an asynchronous, remote environment
- Prior experience with data annotation, data quality frameworks, or evaluation systems (nice to have)
- Background in AI, digital health, or clinical decision support tools (nice to have)
- Experience across multiple therapeutic areas or trial phases (nice to have)
- Familiarity with ICH guidelines, GCP standards, or submission dossier preparation (nice to have)
Salary (Rate): £32.00 hourly
City: Birmingham
Country: United Kingdom
Working Arrangements: remote
IR35 Status: undetermined
Seniority Level: Senior
Industry: IT
Principal Clinical Scientist (AI Training)
About The Role
What if your decades of clinical trial expertise could directly influence how AI reasons about medical evidence, regulatory submissions, and patient outcomes? We're looking for a Principal Clinical Scientist to bring senior-level rigor to one of the most consequential frontiers in technology — AI systems that interpret and generate clinical data. This is a fully remote, flexible contract role built for experienced clinical scientists who want to make an outsized impact without the constraints of a traditional position. You'll work alongside leading AI research labs to ensure that frontier models handle clinical evidence the way regulators — and patients — deserve.
Organization: Alignerr
Type: Hourly Contract
Location: Remote
Commitment: 10–40 hours/week
What You'll Do
- Design and critically review clinical trial protocols used to generate high-quality, regulator-ready training datasets for AI systems
- Interpret and audit clinical trial results to ensure accuracy, consistency, and alignment with regulatory standards (FDA, EMA, or equivalent)
- Evaluate AI-generated clinical analyses for scientific soundness and regulatory relevance — catching errors that only a seasoned expert would spot
- Provide structured, expert feedback that directly shapes how AI models reason about clinical trial design, data, and outcomes
- Help establish the gold standard for how AI understands and communicates clinical evidence
Who You Are
- Senior-level clinical scientist with hands-on experience designing clinical trial protocols for regulatory submission
- Deep expertise interpreting clinical data for regulatory agencies such as the FDA, EMA, or equivalent bodies
- Strong grounding in clinical research methodology, biostatistics, or translational science
- Naturally detail-oriented — you hold clinical evidence to the highest standard and notice when something doesn't hold up
- Comfortable working independently in an asynchronous, remote environment
Nice to Have
- Prior experience with data annotation, data quality frameworks, or evaluation systems
- Background in AI, digital health, or clinical decision support tools
- Experience across multiple therapeutic areas or trial phases
- Familiarity with ICH guidelines, GCP standards, or submission dossier preparation
Why Join Us
- Work directly on frontier AI systems that will shape the future of clinical and biomedical research
- Fully remote and flexible — structure your work around your life, not the other way around
- Freelance autonomy with the substance of genuinely meaningful, high-stakes work
- Influence how AI systems understand, evaluate, and communicate real-world clinical evidence at scale
- Collaborate with world-class AI research teams and labs on cutting-edge projects
- Potential for ongoing work and contract extension as new projects launch