Position Summary
We are seeking a highly experienced ETO Architect to provide architecture leadership for the Manufacturing workstream of the MBD Divestiture program within a global healthcare/life sciences organization.
The ETO Architect will be responsible for defining and governing the technology architecture required to separate, transition, and establish manufacturing capabilities as part of the divestiture. The role will work across Manufacturing, IT/OT, Infrastructure, Applications, ERP, MES, Quality, Supply Chain, Cybersecurity, Integration, Data, and Site IT teams to ensure manufacturing operations can transition successfully without disruption to business-critical and regulated processes.
The ideal candidate will have strong experience supporting manufacturing environments within healthcare, life sciences, pharmaceutical, medical device, or other highly regulated industries, along with hands-on architecture experience in large-scale M&A, divestiture, carve-out, TSA exit, or enterprise transformation programs.
Key Responsibilities
Manufacturing Architecture
Own and drive the overall technology architecture for the Manufacturing workstream within the MBD Divestiture program.
Assess the current-state manufacturing technology landscape and define target-state and transitional architectures required for separation.
Develop architecture covering manufacturing applications, infrastructure, integrations, data, security, network connectivity, and IT/OT dependencies.
Identify systems and technologies that must be retained, separated, migrated, replicated, replaced, or decommissioned as part of the divestiture.
Ensure architecture decisions support manufacturing continuity, scalability, security, compliance, and operational readiness.
Provide architecture guidance across multiple manufacturing sites and technology platforms.
Divestiture & Carve-Out
Translate divestiture requirements into executable technology architecture and separation strategies.
Identify architecture dependencies associated with Day 1 readiness, TSA services, TSA exit, cutover, and future-state operations.
Support application and infrastructure disposition decisions, including migrate, clone, replace, retire, and retain strategies.
Identify shared services, applications, integrations, infrastructure, and data dependencies between the divested organization and the parent company.
Define interim architectures where systems or services must continue operating under TSA arrangements.
Partner with program and workstream leadership to manage architecture risks, assumptions, dependencies, and technical decisions.
Support cutover planning and ensure manufacturing architecture is ready for key separation milestones.
Manufacturing Systems & IT/OT
Provide architectural oversight for manufacturing technology environments, including systems such as:
Manufacturing Execution Systems (MES)
ERP and manufacturing modules
Laboratory and Quality systems
SCADA / industrial systems
Historian platforms
Equipment and shop-floor integrations
Warehouse and inventory systems
Serialization and labeling platforms
Manufacturing data and reporting platforms
Understand dependencies between IT and OT environments, including plant networks, servers, manufacturing equipment, interfaces, security zones, and connectivity.
Work closely with plant/site IT and manufacturing engineering teams to minimize operational disruption during transition activities.
Application, Integration & Data Architecture
Review application inventories and identify critical manufacturing application dependencies.
Define integration architecture across ERP, MES, Quality, Supply Chain, Warehouse, Laboratory, and other manufacturing platforms.
Assess interfaces with enterprise and external systems and determine appropriate separation or migration strategies.
Define data migration, replication, archival, retention, and separation requirements.
Ensure appropriate handling of manufacturing master data, transactional data, quality records, batch information, and regulated records.
Support interface remediation and integration testing associated with application separation.
Infrastructure & Security Architecture
Collaborate with infrastructure teams on architecture for:
Networks and connectivity
Servers and virtualization
Cloud platforms
Storage and backup
Identity and Access Management (IAM)
End-user computing
Disaster recovery and business continuity
Define connectivity requirements between manufacturing sites and enterprise platforms during and after separation.
Partner with Cybersecurity teams to ensure appropriate segmentation, access controls, security standards, and risk remediation.
Ensure manufacturing environments remain secure and operational throughout the divestiture transition.
Healthcare / Life Sciences Compliance
Ensure architecture decisions consider requirements associated with regulated healthcare and life sciences manufacturing environments.
Work with Quality, Compliance, Validation, and Cybersecurity teams to ensure solutions meet applicable regulatory and organizational requirements.
Understand considerations related to GxP/GMP, Computer System Validation (CSV), data integrity, audit trails, electronic records, and controlled manufacturing environments.
Ensure technology changes are implemented through appropriate change-control and validation processes where required.
Assess the regulatory and operational impact of architecture changes before implementation.
Architecture Governance & Documentation
Develop and maintain architecture deliverables including:
Current-state architecture
Target-state architecture
Transitional architecture
Application and infrastructure dependency maps
Integration diagrams
Data-flow diagrams
Technology disposition recommendations
Architecture Decision Records (ADRs)
Separation and transition architecture
Lead architecture reviews and obtain alignment from technical and business stakeholders.
Maintain traceability between business requirements, manufacturing requirements, architecture decisions, and implementation plans.
Identify technical risks early and drive appropriate mitigation strategies.
Required Qualifications
- 12+ years of overall IT experience, with significant experience in Enterprise/Solution/Technology Architecture.
- 5+ years of strong architecture experience supporting Manufacturing technology environments.
- 5+ years of demonstrated experience working on M&A, divestiture, carve-out, business separation, TSA exit, or large-scale transformation programs.
- Strong understanding of manufacturing applications, infrastructure, integrations, data, and IT/OT environments.
- Experience defining current-state, transitional, and target-state architectures.
- Experience working with ERP, MES, manufacturing, Quality, Supply Chain, Warehouse, and related enterprise systems.
- Strong understanding of application and infrastructure dependencies within manufacturing environments.
- Experience with enterprise integration patterns, APIs, middleware, interfaces, and data flows.
- Good understanding of networking, cloud, infrastructure, IAM, cybersecurity, and business continuity.
- Strong architecture governance and technical documentation skills.
- Ability to work across multiple workstreams, sites, vendors, and geographically distributed teams.
- Excellent stakeholder management and communication skills, with the ability to communicate complex architecture topics to both technical and business stakeholders.
Industry Experience
Healthcare / Life Sciences experience is strongly preferred, particularly within:
Pharmaceutical manufacturing
Medical devices
Diagnostics
Biotechnology
Laboratory products
Regulated healthcare manufacturing
Candidates should have a strong understanding of the operational and regulatory considerations associated with technology changes in regulated manufacturing environments.
Preferred Qualifications
- Prior experience as an Enterprise Architect, Technology Architect, Solution Architect, or Manufacturing Architect on a major divestiture or M&A program.
- Experience supporting Day 1, TSA, TSA exit, cutover, and post-separation stabilization.
- Experience with SAP or other enterprise ERP platforms in manufacturing environments.
- Experience with MES and shop-floor/manufacturing system integrations.
- Understanding of ISA-95 architecture and IT/OT integration principles.
- Experience with cloud and hybrid infrastructure environments.
- Knowledge of GxP, GMP, CSV/CSA, data integrity, and regulated system lifecycle requirements.
- Experience supporting global manufacturing sites and large-scale transformation programs.
Key Skills
Must Have:
Enterprise / Solution Architecture
Manufacturing Technology Architecture
Manufacturing IT/OT
M&A / Divestiture / Carve-Out
Application Separation & Migration
ERP / MES Architecture
Integration Architecture
Infrastructure Architecture
Data & System Dependency Mapping
TSA / TSA Exit Planning
Cutover & Transition Architecture
Architecture Governance
Healthcare / Life Sciences or Regulated Manufacturing
Good to Have:
SAP
MES / Manufacturing Systems
ISA-95
GxP / GMP
CSV / CSA
Cloud Architecture
Cybersecurity / Network Segmentation
Data Migration
Quality & Laboratory Systems